
Oreon Life Science
aesPlla
Brand
Oreon Life Science
Category
Biostimulator (PLLA/PCL)
Origin
Korea
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Overview
aesPlla is a pure poly-L-lactic acid (PLLA) collagen stimulator from Korean company Oreon Life Science, supplied as a 365 mg lyophilised powder. It contains no immediate-fill component, instead driving gradual collagen regeneration for natural, progressive correction. It is CE-marked and positioned for practitioners seeking a high-payload PLLA biostimulator.
How it works
Reconstituted PLLA microparticles are placed in the deep dermis and hypodermis where they act as a biodegradable scaffold, prompting fibroblasts to produce new type-I collagen over the following weeks and months. The PLLA polymer is gradually resorbed while the newly formed collagen provides progressive volumisation and smoothing.
Indications
- Collagen loss and skin laxity
- Facial wrinkles and nasolabial folds
- Volume deficiency in temples, cheeks and marionette lines
- Facial rejuvenation and contour restoration
Key features
- Pure PLLA formulation with no HA fill component
- High 365 mg payload per vial
- Biocompatible, biodegradable synthetic polymer
- Suited to linear-threading deep dermal and hypodermal placement
- CE-marked
Benefits
- High payload supports broad-area collagen rebuilding per vial
- Gradual, natural correction differentiates from immediate-fill products
- Long reported duration supports patient value proposition
- Established Korean manufacturer for clinic and distributor sourcing
Composition
Poly-L-lactic acid (PLLA) 365 mg per vial as lyophilised powder; no hyaluronic acid. Reconstituted with approximately 5 mL sterile water.
Usage & handling
Reconstitute with approximately 5 mL sterile water (18G needle) and allow the suspension to hydrate; use within about 72 hours of preparation. Inject via linear-threading into the deep dermis and hypodermis using a cannula or needle. Results typically emerge from around 4 weeks and continue to build over subsequent months; space sessions per protocol, with reported longevity up to about 3 years.
For medical professionals. Product information is for reference and does not replace the manufacturer's instructions for use. Availability and regulatory status vary by region.