REGEN Biotech
Aesthefill
Brand
REGEN Biotech
Category
Biostimulator (PLLA/PCL)
Origin
Korea
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Overview
AestheFill is a poly-D,L-lactic acid (PDLLA) microsphere collagen stimulator from Korean manufacturer REGEN Biotech. Its sponge-like porous microspheres allow new collagen to form both around and within each particle, driving progressive, natural rejuvenation. The powder requires only a short reconstitution and comparatively little water relative to older PLLA products.
How it works
The porous PDLLA microspheres are injected into the dermal or subdermal layers where they act as a scaffold, triggering a controlled fibroblast response. New type-I collagen grows around and inside each sponge-like particle over several months; the PDLLA is biocompatible and biodegradable and resorbs over time while the induced collagen persists for durable correction.
Indications
- Facial volume loss
- Deep wrinkles and folds, including nasolabial folds
- Skin laxity and loss of firmness
- Facial rejuvenation and crepey skin
Key features
- Sponge-like porous PDLLA microspheres
- Collagen forms both around and inside each particle
- Short reconstitution time with little water required
- Biocompatible and biodegradable microsphere scaffold
- Manufactured by REGEN Biotech
Benefits
- Faster, simpler reconstitution than older PLLA products streamlines preparation
- Progressive, natural-looking neocollagenesis supports patient satisfaction
- Long reported duration strengthens the treatment value proposition
- Established Korean manufacturer with international distribution
Composition
Poly-D,L-lactic acid (PDLLA) porous microspheres supplied as lyophilised powder for reconstitution. (Per-vial milligram content is not stated on the manufacturer page.)
Usage & handling
Reconstitute the lyophilised powder, which REGEN Biotech notes requires only a short reconstitution time and little water; hydrate per protocol before injecting into the deep dermis or subdermis. Gradual results begin around 4-6 weeks with peak effect at roughly 3-6 months and reported longevity of about 18-24 months; space repeat sessions per clinical response.
For medical professionals. Product information is for reference and does not replace the manufacturer's instructions for use. Availability and regulatory status vary by region.