BluDerma
Powerfill

Regen Biotech

Powerfill

Brand

Regen Biotech

Category

Biostimulator (PLLA/PCL)

Origin

Korea

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Overview

Powerfill is a South Korean poly-D,L-lactic acid (PDLLA) collagen biostimulator from Regen Biotech, supplied as a 1000 mg lyophilised powder for reconstitution. It is positioned for larger-area and body contouring where gradual, natural-looking volume restoration is required. Rather than acting as an instant filler, it drives the patient's own collagen synthesis over the following weeks and months.

How it works

Once reconstituted and injected, the PDLLA microspheres act as a biocompatible scaffold that provokes a controlled fibroblast response, prompting deposition of new type I and III collagen. The carrier gel is resorbed within weeks while the collagen matrix continues to build, producing progressive volume and dermal thickening. Full results develop over a multi-session course as neocollagenesis matures.

Indications

  • Facial and body skin laxity
  • Age-related collagen loss and volume depletion
  • Body contouring and large-area volumisation
  • Decolletage and other broad rejuvenation areas
  • Overall skin quality and dermal thickening

Key features

  • Poly-D,L-lactic acid (PDLLA) microsphere biostimulator
  • High 1000 mg payload suited to larger areas and body contouring
  • Lyophilised format reconstituted at point of care
  • Gradual biostimulatory volume rather than instant fill
  • For use by licensed practitioners only

Benefits

  • Extends the regenerative/biostimulator menu beyond HA fillers
  • Large-volume vial is economical for body and broad-area treatments
  • Natural, progressive results support patient retention and repeat courses
  • Fully resorbable synthetic based on well-established PLA chemistry
  • Manufactured by Regen Biotech, an established Korean PLA specialist

Composition

Poly-D,L-lactic acid (PDLLA) microspheres, 1000 mg lyophilised powder per vial, with sodium carboxymethylcellulose (CMC); reconstituted before use.

Usage & handling

Reconstitute the lyophilised powder with sterile water and allow adequate hydration time before injection. Inject into the deep dermis or subcutaneous plane; avoid superficial placement. Massage after treatment to distribute product evenly. Results build over weeks to months and a multi-session protocol is typical.

For medical professionals. Product information is for reference and does not replace the manufacturer's instructions for use. Availability and regulatory status vary by region.